Effects of an adrenocortical extract on tissue glycolysis in vitro.
نویسنده
چکیده
Several investigators have reported that a commercial adrenal extract, Lipo-Adrenal Cortex,’ possesses marked lymphocytolytic action in vitro not manifested by other preparations (l-3). In the hope of correlating this finding with a change in some specific metabolic function, we have investigated the influence of this preparation on tissue metabolism in vitro. The results obtained indicate that L. A. C. produces a marked increase in aerobic glycolysis, and that this effect cannot be attributed to cortical steroids oxygenated at carbon 11, which are known to be present. Correlations of this phenomenon with lymphocytolytic response to L. A. C. are reported elsewhere (4).
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ورودعنوان ژورنال:
- The Journal of biological chemistry
دوره 208 1 شماره
صفحات -
تاریخ انتشار 1954